Mechanistic Studies of Homo- and Heterodinuclear Zinc Phosphoesterase Mimics: What Has Been Learned?
Phosphoesterases hydrolyze the phosphorus oxygen bond of phosphomono-, di- or triesters and are involved in various important biological processes.Carboxylate and/or hydroxido-bridged dizinc(II) sites are a widespread structural motif in this enzyme class.Much effort has been invested to unravel the Creamers mechanistic features that provide the en